Closing the Loop: Multi-Disciplinary Strategies for Reducing Diagnostic Error in Acute Care

Zainab Hussein Alhassan (1), Abdullah Samah Almutairi (2), Faisl Mohammed Hamad Alotaibi (3), Ahmed Raji Alanazi (4), Fatem Hassan Yahya Madkhali (5), Sultan Mohammed Ibrahim Aati (6), Mohammad Ali Mahzari , Ali Marzoug Ayed Almashely (7), Zahara Salman Hamid Almaqadi (8), Noha Abdullah Alanazi (9), Rahmah Ahmed Mughram Alamri (10), Reem Hajad Shabwan Alshamrani (11), Nesren Ageel Bashkoor (12), Mohammed Nefal Aldosari (13)
(1) 1Al-Umran General Hospital, Al-Ahsa, Ministry of Health, Saudi Arabia,
(2) King Khaled General Hospital, Ministry of Health, Saudi Arabia,
(3) Branch of the Ministry of Health in Riyadh Region, Saudi Arabia,
(4) Al-Yamamah Hospital,Ministry Of Health, Saudi Arabia,
(5) Al-Jadi Hospital, Jazan,Ministry Of Health, Saudi Arabia,
(6) Chest Diseases Hospital, Jazan Health Cluster – Jazan, Ministry Of Health, Saudi Arabia,
(7) Tathleeth General Hospital, Ministry of Health, South Africa,
(8) Ministry Of Health, Saudi Arabia,
(9) Al-Nasifah Health Center in Al-Kharj,Ministry of Health, Saudi Arabia,
(10) Al Majardah General Hospital,Ministry of Health, Saudi Arabia,
(11) Aseer Health Cluster - Bisha Domain - Command and Control Department,Ministry of Health, Saudi Arabia,
(12) Erada Mental Health Hospital,Ministry of Health, Saudi Arabia,
(13) Al-Maathar Housing Health Center,Ministry of Health, Saudi Arabia

Abstract

Background: Diagnostic error in acute care represents a pervasive threat to patient safety, contributing to significant morbidity, mortality, and healthcare costs. These failures are rarely due to individual incompetence but are systemic, arising from complex interactions across the care continuum—from prehospital assessment to specialist interpretation and follow-up. Aim: This narrative review aims to synthesize evidence on multi-disciplinary, system-oriented strategies for reducing diagnostic error in acute settings, integrating the unique perspectives and interventions of clinical laboratory science, medical imaging, emergency medical services, nursing, social work, preventive medicine, public health, and health security. Methods: A comprehensive literature search of PubMed, Scopus, CINAHL, and PsycINFO databases (2010-2024) was conducted. Included studies, reviews, and grey literature were analyzed thematically to construct a narrative synthesis of collaborative error-reduction frameworks. Results: Effective strategies form an interdependent "safety loop." Critical components include standardized handoff protocols (EMS), structured result communication and "second-look" practices (lab/radiology), nursing clinical surveillance, social work-mediated health literacy interventions, preventive medicine-led quality improvement cycles, public health surveillance of error trends, and health security principles fostering a just culture of reporting. Conclusion: Mitigating diagnostic error requires moving beyond siloed solutions to implement integrated, multi-professional systems. A culture of psychological safety, supported by structured communication and continuous learning, is essential for closing the diagnostic loop and ensuring reliable acute care.

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Authors

Zainab Hussein Alhassan
zhalhassan1@gmail.com (Primary Contact)
Abdullah Samah Almutairi
Faisl Mohammed Hamad Alotaibi
Ahmed Raji Alanazi
Fatem Hassan Yahya Madkhali
Sultan Mohammed Ibrahim Aati
Mohammad Ali Mahzari
Ali Marzoug Ayed Almashely
Zahara Salman Hamid Almaqadi
Noha Abdullah Alanazi
Rahmah Ahmed Mughram Alamri
Reem Hajad Shabwan Alshamrani
Nesren Ageel Bashkoor
Mohammed Nefal Aldosari
Alhassan, Z. H., Abdullah Samah Almutairi, Faisl Mohammed Hamad Alotaibi, Ahmed Raji Alanazi, Fatem Hassan Yahya Madkhali, Sultan Mohammed Ibrahim Aati, … Mohammed Nefal Aldosari. (2024). Closing the Loop: Multi-Disciplinary Strategies for Reducing Diagnostic Error in Acute Care. Saudi Journal of Medicine and Public Health, 1(2), 2145–2150. https://doi.org/10.64483/202412599

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