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Vol. 1 No. 2 (2024)

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February 8, 2026
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December 31, 2024

Copyright (c) 2024 Sultan Rakkad Halwan Alsharari, Abdulrahman Ayed Fazzaa Alsharari, Bader Awwadh Dablan Alamri, Abeer Musabbih Salamah Alsharari, Mujahid Azim Dhumran Alsharari, Rawan Saud Alahmadi, Nada Hamdan Ghamshi, Abdulaziz Mohammed Almoies, Saad Dhafer Alqahtani, Manal Ali Hassan Makin, Fairouz Hassan Ahead Jobahe, Mohammed Ali Makin

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Cardio-Pulmonary Oncology Surveillance: Integrating Advanced Cardiac Imaging, Biomarker Panels, and Nurse-Respiratory Therapist Coordinated Care

https://doi.org/10.64483/202412639
Sultan Rakkad Halwan Alsharari
Al-Qurayyat General Hospital, Al-Qurayyat, Al-Jawf Health Cluster, Ministry of Health, Saudi Arabia
Abdulrahman Ayed Fazzaa Alsharari
Al-Issawiyah General Hospital, Al-Issawiyah, Al-Jawf Health Cluster, Ministry of Health, Saudi Arabia
Bader Awwadh Dablan Alamri
King Fahd Hospital in Madinah, Madinah, Madinah Health Cluster, Ministry of Health, Saudi Arabia
Abeer Musabbih Salamah Alsharari
Al-Issawiyah General Hospital, Al-Issawiyah, Al-Jawf Health Cluster, Ministry of Health, Saudi Arabia
Mujahid Azim Dhumran Alsharari
Al-Issawiyah General Hospital, Al-Issawiyah, Al-Jawf Health Cluster, Ministry of Health, Saudi Arabia
Rawan Saud Alahmadi
Regional Laboratory – Madinah, Ministry of Health, Saudi Arabia
Nada Hamdan Ghamshi
King Salman Hospital – Riyadh, Ministry of Health, Saudi Arabia
Abdulaziz Mohammed Almoies
King Salman Hospital – Riyadh, Ministry of Health, Saudi Arabia
Saad Dhafer Alqahtani
Prince Sultan Health Center – Al-Ahmadiyah, Ministry of Health, Saudi Arabia
Manal Ali Hassan Makin
King Fahad Hospital, Ministry of Health, Saudi Arabia
Fairouz Hassan Ahmed Jobahe
Primary Health Care Center, Damad Alshamali, Ministry of Health, Saudi Arabia
Mohammed Ali Makin
South Qunfudah Hospital, Ministry of Health, Saudi Arabia

Corresponding Author(s) : Sultan Rakkad Halwan Alsharari

Salshrariy@moh.gov.sa

Saudi Journal of Medicine and Public Health, Vol. 1 No. 2 (2024)

Abstract

Background: The success of modern cancer therapeutics has created a growing population of survivors at risk for multisystem toxicity, notably cancer therapy-related cardiac dysfunction (CTRCD) and pulmonary complications such as pneumonitis, fibrosis, and pulmonary hypertension. These cardiopulmonary toxicities often coexist, share common pathophysiological pathways, and require coordinated multidisciplinary surveillance. Aim: This narrative review synthesizes evidence to propose an integrative surveillance model combining advanced cardiac imaging (echocardiography with strain, cardiac MRI), pulmonary function assessment, circulating biomarker panels, and structured nurse-respiratory therapist coordinated care for early detection and management of cardiopulmonary toxicity. Methods: A comprehensive literature review was conducted using PubMed, Scopus, and CINAHL for studies (2010-2024) on imaging, biomarkers, and interdisciplinary care models in cardio-pulmonary oncology. Results: Evidence supports a multimodal approach: echocardiography with global longitudinal strain (GLS) and cardiac MRI detect myocardial dysfunction; pulmonary function tests (PFTs) and diffusion capacity (DLCO) identify restrictive patterns; serial biomarkers (hs-troponin, BNP, KL-6, SP-D) provide early biochemical warning. Nurse-respiratory therapist co-led clinics improve symptom assessment, patient education, pulmonary rehabilitation, and timely intervention, preserving functional capacity and quality of life. Conclusion: An integrated, nurse-respiratory therapist coordinated surveillance pathway utilizing advanced cardiopulmonary imaging, biomarker monitoring, and functional assessment is essential for mitigating multisystem toxicity and optimizing survivorship outcomes.

Keywords

Cardio-Oncology, Pulmonary Oncology, Cardiac Imaging, Respiratory Therapy, Interdisciplinary Care
Alsharari, S. R. H., Alsharari, A. A. F., Alamri, B. A. D., Alsharari, A. M. S., Alsharari, M. A. D., Alahmadi, R. S., … Makin, M. A. (2024). Cardio-Pulmonary Oncology Surveillance: Integrating Advanced Cardiac Imaging, Biomarker Panels, and Nurse-Respiratory Therapist Coordinated Care. Saudi Journal of Medicine and Public Health, 1(2), 2306–2312. https://doi.org/10.64483/202412639
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