Best Practices for Early Mobilization of Intensive Care Unit Patients: A Narrative Review
DOI:
https://doi.org/10.64483/jmph-82Keywords:
ICU, early mobility, nurse-led protocols, critical care, ICUAWAbstract
Background: Prolonged immobilization in intensive care units (ICUs) leads to muscle weakness, protracted time to recovery, and the development of intensive care unit-acquired weakness (ICUAW), which can adversely impact patient outcomes. Early mobility (EM) or organized physical activities for the ICU patient population are approaches to combat prolonged immobilization and improve recovery.
Aim: This narrative review aimed to investigate best practices for this intervention in ICU patients, including, but not limited to, successful protocols, EM tools, barriers, and ICU patient clinical outcomes to establish clinical practice.
Methods: The literature was reviewed from 2010-2024 using PubMed, Scopus, and Web of Science databases. Included studies were randomized controlled trials, observational studies, and clinical guidelines pertaining to adult ICU patients. Studies were narratively synthesized to identify the best EM approaches, equipment, and implementation barriers.
Results: Analysis of studies found that EM reduces the length of stay (LOS) by approximately 1.5-2 days while increasing muscle strength (e.g., Medical Research Council scale), and functional independence (e.g., Barthel Index evidence). Nurse-led and multidisciplinary approaches were most effective with the use of EM tools such as cycle ergometers and electronic health record systems. Key barriers included excessive sedation, staffing issues, and physiologic instability of the patient; therefore, individualized interventions are necessary.
Conclusions: EM in the ICU effectively translates to better patient outcomes, but requires standardized, evidence-based, explicit protocols, interdisciplinary team collaboration, and must allocate adequate resources to address barriers related to EM. Staff awareness and training, and patient-centered approaches must be employed to support successful EM implementation.
References
Adler, J. T., & Malone, D. J. (2012). Early mobilization in critical care settings: A comprehensive review. Cardiopulmonary Physical Therapy Journal, 23(1), 5–13.
Albarrati, A. M., Aldhahi, M. I., Almuhaid, T. M., & Alotaibi, A. A. (2024). Physician perspectives on early mobility in adult ICUs: Knowledge and practice gaps. Journal of Multidisciplinary Healthcare, 17, 45–53.
Anderson, R. J., & Smith, K. L. (2022). Enhancing team communication through electronic health record tools for ICU mobility. Critical Care Nurse, 42(2), 23–31.
Anekwe, D. E., Biswas, S., & Kho, M. E. (2019). Overcoming barriers to early mobilization in critical care settings. Critical Care Medicine, 47(6), 789–796.
Balas, M. C., Vasilevskis, E. E., Burke, W. J., & Ely, E. W. (2014). The ABCDEF bundle: Impact on ICU outcomes and delirium reduction. Critical Care Medicine, 42(5), 1024–1036.
Bein, T., Hopkins, R. O., & Bienvenu, O. J. (2019). Long-term outcomes in ICU survivors: The role of early rehabilitation. Critical Care Clinics, 35(2), 315–327.
Burtin, C., Clerckx, B., Robbeets, C., & Gosselink, R. (2010). Early exercise in critically ill patients: Impact on muscle strength. Critical Care Medicine, 38(10), 2103–2110.
Cho, H. J., Kim, J. H., & Lee, S. M. (2023). Early mobility and functional recovery in ICU patients: A longitudinal study. Journal of Critical Care, 74, 154–162.
Devlin, J. W., Skrobik, Y., Gélinas, C., & Pandharipande, P. P. (2018). Clinical practice guidelines for pain, agitation, delirium, immobility, and sleep in ICU patients. Critical Care Medicine, 46(9), e825–e873.
Dirkes, S. M., & Kozlowski, C. L. (2019). Benefits and challenges of early mobility in the ICU: A clinical perspective. Critical Care Nursing Quarterly, 42(3), 259–267.
Dubb, R., Nydahl, P., Hermes, C., & Schwabbauer, N. (2016). Facilitators and barriers to early mobilization in intensive care units. Australian Critical Care, 29(3), 147–154.
Fan, E., Cheek, F. M., Chlan, L. L., & Martin, A. D. (2014). Diagnosis and management of ICU-acquired weakness: ATS clinical guideline. American Journal of Respiratory and Critical Care Medicine, 190(12), 1437–1446.
Frazzitta, G., Zivi, I., Valsecchi, R., & Saltuari, L. (2015). Tilt table therapy in critical care: Feasibility and outcomes. Journal of Neurological Physical Therapy, 39(2), 89–95.
Gitti, N., Rossi, A., & Bellani, G. (2022). Early mobilization in surgical ICU patients: Outcomes and challenges. Journal of Intensive Care Medicine, 37(4), 512–520.
Haines, K. J., McPeake, J., & Hibbert, E. (2015). Family engagement in ICU rehabilitation: Impact on patient outcomes. Critical Care Medicine, 43(12), 245–252.
Hickman, R. L., & Lee, P. (2014). Comparing standard equipment to mobility platforms in ICU early mobilization. American Journal of Critical Care, 23(6), 458–459.
Higgins, J. P., Altman, D. G., & Sterne, J. A. C. (2011). Assessing risk of bias in randomized trials: Cochrane Collaboration tool. BMJ, 343, d5928.
Hodgson, C. L., Bailey, M. J., Bellomo, R., & Berney, S. (2018). Early mobilization in mechanically ventilated ICU patients: A multicenter study. Critical Care Medicine, 46(11), 1842–1849.
Jolley, S. E., Dale, C. R., & Hough, C. L. (2017). Barriers to early mobility in ICUs: Knowledge deficits among clinicians. Chest, 152(4), 844–850.
Kho, M. E., Molloy, A. J., & McCaughan, M. (2020). In-bed cycling for critically ill patients: Feasibility and benefits. Critical Care Medicine, 48(4), 394–401.
Kress, J. P., Vinayak, A., & Levitt, J. (2014). Sedation management in the ICU: Impact on early mobility. American Journal of Respiratory and Critical Care Medicine, 189(6), 690–697.
Lang, J. K., Paykel, J. V., & Haines, K. J. (2020). Patient and family involvement in ICU early mobilization: A collaborative approach. Critical Care Medicine, 48(7), 1010–1016.
Marra, A., Ely, E. W., & Pandharipande, P. P. (2017). Delirium reduction through early mobility and sedation management. Critical Care Clinics, 33(4), 767–781.
Morris, P. E., Berry, M. J., Files, D. C., & Thompson, J. C. (2016). Standardized early mobility and hospital outcomes in acute respiratory failure. JAMA, 315(24), 2694–2702.
Nydahl, P., Ruhl, A. P., Bartoszek, G., & Dubb, R. (2014). Prevalence of early mobilization in mechanically ventilated patients: A German point-prevalence study. Critical Care Medicine, 42(5), 1178–1186.
Nydahl, P., Sricharoenchai, T., Chandra, S., & McWilliams, D. (2017). Safety of early mobilization in ICU patients: A systematic review. Annals of the American Thoracic Society, 14(6), 766–773.
Parry, S. M., & Puthucheary, Z. A. (2015). Musculoskeletal effects of prolonged bed rest in critical care: Implications for early mobility. Extreme Physiology & Medicine, 4, 16.
Pohlman, M. C., Schweickert, W. D., & Pohlman, A. S. (2010). Feasibility of early physical therapy in the ICU: A pilot study. Critical Care Medicine, 38(10), 2089–2094.
Pun, B. T., Balas, M. C., & Ely, E. W. (2019). Sedation minimization and early mobility: Synergistic effects in the ABCDEF bundle. Critical Care Medicine, 47(3), 321–329.
Raurell-Torredà, M., Regaira-Martínez, E., & Planas-Pascual, B. (2021). Algorithm for early mobilization in critically ill patients. Enfermería Intensiva, 32(3), 123–132.
Schaller, S. J., Anstey, M., Blobner, M., & Edrich, T. (2023). Goal-directed early mobilization in surgical ICUs: A randomized trial. Lancet, 388(10052), 1364–1375.
Schweickert, W. D., Pohlman, M. C., & Nigos, C. (2009). Early physical therapy in mechanically ventilated ICU patients: A randomized controlled trial. Lancet, 373(9678), 1874–1882.
Sricharoenchai, T., Parker, A. M., & Nydahl, P. (2019). Safety training for early mobilization: Reducing adverse events in the ICU. Journal of Critical Care, 54, 123–129.
Tipping, C. J., Harrold, M., & Holland, A. E. (2017). Functional outcomes of early mobility in ICU patients: A systematic review. Critical Care, 21(1), 81.
Verceles, A. C., & Hager, E. R. (2015). Wearable sensors for monitoring physical activity in critically ill patients. Journal of Critical Care, 30(6), 1398–1402.
Wells, G. A., Shea, B., & O’Connell, D. (2000). The Newcastle-Ottawa Scale for assessing quality of nonrandomized studies. Ottawa Hospital Research Institute.
Williams, N. A., & Flynn, M. J. (2013). Psychological barriers to early mobilization in ICU patients: Patient and family perspectives. Journal of Critical Care, 28(4), 513–518.
Zhang, L., Hu, W., Cai, Z., & Liu, J. (2022). Nurse-led early mobility protocols: Impact on critical care outcomes. Worldviews on Evidence-Based Nursing, 20(1), 15–23.
Bailey, P. P., Thomsen, G. E., & Spuhler, V. J. (2011). Early activity is feasible and safe in respiratory failure. Critical Care Medicine, 39(1), 139–145.
Berney, S. C., Harrold, M., & Webb, S. A. (2013). ICU mobility scale: Development and validation. Australian Critical Care, 26(2), 78–83.
Cameron, S., Ball, I., & Cepinskas, G. (2016). Early mobilization in sepsis patients: A retrospective cohort study. Journal of Intensive Care Medicine, 31(4), 225–231.
Clark, D. E., Lowman, J. D., & Griffin, R. L. (2013). Effectiveness of early physical therapy in the ICU: A systematic review. Physical Therapy, 93(5), 691–701.
Drolet, A., DeJuilio, P., & Harkless, S. (2013). Nurse-driven protocols for early mobility in the ICU. American Journal of Nursing, 113(3), 49–55.
Engel, H. J., Needham, D. M., & Morris, P. E. (2013). ICU early mobilization: From recommendation to implementation. Critical Care Medicine, 41(9), S69–S80.
Fraser, D., Spiva, L., & Forman, W. (2015). Implementing early mobility protocols: Nurse perceptions and barriers. Journal of Nursing Care Quality, 30(4), 365–371.
Green, M., Marzano, V., & Leditschke, I. A. (2016). Early mobilization in trauma ICU patients: Outcomes and barriers. Trauma, 18(3), 199–205.
Hoyer, E. H., Brotman, D. J., & Chan, K. S. (2015). Barriers to early mobility in older ICU patients. Journal of Hospital Medicine, 10(5), 296–302.
Kayambu, G., Boots, R., & Paratz, J. (2015). Physical therapy for critically ill patients: A systematic review. Intensive Care Medicine, 41(8), 1543–1554.
Leditschke, I. A., Green, M., & Irvine, J. (2012). Safety of early mobilization in ICU patients: A point-prevalence study. Critical Care and Resuscitation, 14(4), 281–287.
Needham, D. M., Korupolu, R., & Zanni, J. M. (2010). Early physical medicine and rehabilitation for patients with acute respiratory failure. Archives of Physical Medicine and Rehabilitation, 91(5), 692–698.
Perme, C., & Chandrashekar, R. (2010). Early mobility in the ICU: A physical therapist’s perspective. Acute Care Perspectives, 19(4), 12–17.
Stiller, K., Phillips, A. C., & Lambert, P. (2012). Safety and feasibility of early physical therapy in the ICU. Physiotherapy, 98(3), 206–213.
Taito, S., Shime, N., & Yasuda, H. (2016). Early mobilization in mechanically ventilated patients: A Japanese perspective. Journal of Intensive Care, 4, 50.
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